This blog explores post-traumatic stress disorder (PTSD) in the context of developing early childhood interventions in low/middle income countries (LMIC’s). Children from LMIC’s have a higher probability rate of experiencing traumatic experiences, yet the vast majority do not have access to efficacious psychological treatments [1]. Improving access to mental health services is one of the grand challenges faced in global mental health research [2]. After outlining the background relevant research into the lifelong effects of adverse childhood experiences (ACE’s), this blog focuses on the benefits and challenges faced within school-based interventions for early childhood PTSD, before finishing with an example of a study of a school based intervention for PTSD in a LMIC that utilises paraprofessionals as facilitators.
Life Course Consequences
Felitti et al.’s 1998 study [3] into adverse childhood experiences retrospectively asked adult participants to identify adversity they experienced during childhood, and explored for correlation with physical health over the life span. There findings demonstrated how adversity experienced during childhood can translate into life-long health, social and cognitive implications, which can ultimately lead to an early death. Although this theoretical framing of trauma emerged from a population of adults from high income countries (HIC’s), studies have demonstrated that the ACE questionnaire also identified that the model applies to LMIC, some of which have particularly high rates of childhood adversity [4].

In extrapolating childhood adversity as an underlying causal factor in later adult health issues, the ACE study also alludes to the positive consequences of interventions that successfully address and resolve the adverse experiences therapeutically. Namely, that the consequences may span beyond immediate improvements to a participant’s mental health, altering their life course trajectory. This life course perspective is also adopted in the justification for increased investment into early childhood interventions [5] [6].
Applying this rationale onto working with children to address PTSD may also represent a valuable return on investment. To give a reductionist example to illustrate the point, it might be cost less to resolve the underlying adverse experiences through therapeutic interventions whilst the individual is still a child, otherwise if they later develop alcoholism, the subsequent remedial medical efforts because of their liver failure may be far more costly compared to the early childhood intervention.
The lack of LMIC research
In a meta analysis of 24 studies, Newman et al. found that psychological interventions, predominantly cognitive behaviour therapy based protocols, are an effective post-disaster treatments for children with PTSD [7]. However, there is a large paucity in research into child and adolescent mental health interventions in LMIC’s compared to HIC’s [8]. Indeed, between 2001 and 2010, 90% of randomised control trials into child and adolescent mental health disorders were on HIC populations [8][1].

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Regarding PTSD, of 1000 reviewed articles containing adult and child populations, only 12.7% contained sample populations outside of HIC’s [9]. making LMIC’s significantly under represented. Furthermore, 57% of the articles were only available through journal subscriptions, demonstrating a barrier to access where LMIC researchers often rely upon open access publications [9].
Why School based?
School based mental health programmes are a key strategy in addressing the paucity of mental health interventions for children in LMIC [1]. In a meta analysis of 19 studies, 8 of which were either LMIC’s or refugee populations, Rolfsnes and Idsoe found that school based interventions have a medium to large effect on reducing symptoms of child PTSD [10] Furthermore, interventions delivered in school settings led to considerably more students accessing and completing free treatment for PTSD after Hurricane Kutrina, compared to treatment in a clinical setting [12]. This highlights how convenience of location and familiarity of setting are factors can affect treatment outcomes, and that placing interventions within the school setting can overcome particular barriers to access.
Challenged with school-based interventions for PTSD in LMIC
Utilising teachers that are already overburdened with their daily tasks and responsibilities is challenge faced with integrating mental health interventions in a school setting [1]. Despite this, studies have found that utilising existing professionals to deliver mental health interventions at schools can be successful [10]. Inadequately trained health care professionals and teachers, as well as parents, with a lack of mental health knowledge is a barrier in identifying and diagnosing children with mental health issues [1]. This is a particularly nuanced challenge, considering how PTSD shares multiple clusters of behaviours and symptoms with other diagnostic classifications, such as depression and anxiety based disorders [11].Furthermore, the fact that individuals will react differently to adversity even when they are shared traumatic experiences, and that not everyone will develop symptoms of PTSD [10], represents further challenges in selection criteria for access to interventions. Indeed, Dybdahl found that children’s symptoms of distress following similar exposures to combat violence widely differed [13].
An Example of school-based child PTSD intervention in LMIC

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In a study of 495 children, with a mean age of 9.9, Tol et al. designed a program of 15 group trauma therapy sessions, for children affected by political violence in Indonesia [14]. The program was manualised, based upon efficacious trauma processing creative activities, and was delivered by trained paraprofessionals after 5 weeks of training.
This simultaneously overcomes the challenge of over-burdened teachers, and the lack of mental health professionals in LMIC’s. Although the study only achieved modest results in decreasing PTSD symptoms of treatment group compared with the waiting list group, and had several methodological limitations, [14] it is included here because it represents a novel intervention design that attempts to overcome barriers to access of mental health interventions, by creating lower cost methods of implementation through the utilisation of paraprofessionals.
Conclusion
This blog has explored the nature of the life course effects of children’s experiences of adversity, whilst highlighting the current paucity in child mental health research in low and middle income countries. School based interventions are a key strategy in improving attendance and outcome in interventions, and utilising paraprofessionals may help to overcome some of the current barriers to scaling the implementation of child PTSD interventions.
Thanks for reading!
References
[1]. Patel, V., Kieling, C., Maulik, P. K., & Divan, G. (2013). Improving access to care for children with mental disorders: a global perspective. Archives of disease in childhood, 98(5), 323-327. http://dx.doi.org/10.1136/archdischild-2012-302079
[2] Collins, P. Y., Patel, V., Joestl, S. S., March, D., Insel, T. R., Daar, A. S., … & Glass, R. I. (2011). Grand challenges in global mental health. Nature, 475(7354), 27-30. https://www.nature.com/articles/475027a
[3] Felitti, V. J., Anda, R. F., Nordenberg, D., Williamson, D. F., Spitz, A. M., Edwards, V., Koss, M. P., & Marks, J. S. (1998). Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults: The Adverse Childhood Experiences (ACE) Study. American Journal of Preventive Medicine, 14(4), 245–258. https://doi.org/10.1016/S0749-3797(98)00017-8
[4]. Manyema, M., & Richter, L. M. (2019). Adverse childhood experiences: prevalence and associated factors among South African young adults. Heliyon, 5(12), e03003. https://doi.org/10.1016/j.heliyon.2019.e03003
[5] Black, M. M., Walker, S. P., Fernald, L. C., Andersen, C. T., DiGirolamo, A. M., Lu, C., … & Devercelli, A. E. (2017). Early childhood development coming of age: science through the life course. The Lancet, 389(10064), 77-90. https://doi.org/10.1016/S0140-6736(16)31389-7
[6]. Doyle, O., Harmon, C. P., Heckman, J. J., & Tremblay, R. E. (2009). Investing in early human development: timing and economic efficiency. Economics & Human Biology, 7(1), 1-6. https://doi.org/10.1016/j.ehb.2009.01.002
[7] Newman, E., Pfefferbaum, B., Kirlic, N., Tett, R., Nelson, S., & Liles, B. (2014). Meta-analytic review of psychological interventions for children survivors of natural and man-made disasters. Current psychiatry reports, 16(9), 462. https://link.springer.com/article/10.1007/s11920-014-0462-z
[8]. Kieling, C., Baker-Henningham, H., Belfer, M., Conti, G., Ertem, I., Omigbodun, O., … & Rahman, A. (2011). Child and adolescent mental health worldwide: evidence for action. The Lancet, 378(9801), 1515-1525. https://doi.org/10.1016/S0140-6736(11)60827-1
[9] Fodor, K. E., Unterhitzenberger, J., Chou, C. Y., Kartal, D., Leistner, S., Milosavljevic, M., … & Alisic, E. (2014). Is traumatic stress research global? A bibliometric analysis. European Journal of Psychotraumatology, 5(1), 23269. https://doi.org/10.3402/ejpt.v5.23269
[10] Rolfsnes, E. S., & Idsoe, T. (2011). School‐based intervention programs for PTSD symptoms: A review and meta‐analysis. Journal of Traumatic Stress, 24(2), 155-165.
https://doi.org/10.1002/jts.20622
[11]Amaya-Jackson, L., Socolar, R. R., Hunter, W., Runyan, D. K., & Colindres, R. (2000). Directly questioning children and adolescents about maltreatment: A review of survey measures used. Journal of Interpersonal Violence, 15(7), 725-759. https://doi.org/10.1177/088626000015007005
[12] Jaycox, L. H., Cohen, J. A., Mannarino, A. P., Walker, D. W., Langley, A. K., Gegenheimer, K. L., … & Schonlau, M. (2010). Children’s mental health care following Hurricane Katrina: A field trial of trauma‐focused psychotherapies. Journal of Traumatic Stress: Official Publication of The International Society for Traumatic Stress Studies, 23(2), 223-231. https://doi.org/10.1002/jts.20518
[13] Dybdahl, R. (2001). Children and mothers in war: an outcome study of a psychosocial intervention program. Child development, 72(4), 1214-1230. https://doi.org/10.1111/1467-8624.00343
[14] Tol, W. A., Komproe, I. H., Susanty, D., Jordans, M. J., Macy, R. D., & De Jong, J. T. (2008). School-based mental health intervention for children affected by political violence in Indonesia: a cluster randomized trial. Jama, 300(6), 655-662. doi:10.1001/jama.300.6.655
[15] Suhartono, M., Victor, D. 2019. Violence Erupts in Indonesia’s Capital in Wake of Presidential Election Results. Retrieved from: https://www.nytimes.com/2019/05/22/world/asia/indonesia-election-riots.html
[16] World Bank. 2016. Country Income Groups (World Bank Classification). Retrieved from: http://chartsbin.com/view/2438











